Accelerating Genome Editing
Innovations with High-Purity gRNA.
- YOUR NEIGHBORHOOD
gRNA PARTNER
FAST, LOCAL SUPPORT - 1 hour from Boston / Cambridge
- EXCEPTIONAL PURITY
- 90%@100mer and more...
- CONSISTENT
QUALITY BENCH TO GMP - Quality without scale gaps
Close to Boston for speed-backed by Japan for scale.
From Marlborough, MA, SC-AMSA delivers high-purity gRNA in research quantities with rapid turnaround. As your program scales, manufacturing can transition to Japan, including GMP supply, using the same amidites and the same manufacturing method, enabling smooth development with minimal tech-transfer friction. For small-volume GMP needs, PeptiStar’s OP100 is available, and for larger volumes, Sumitomo Chemical and PeptiStar offer OPS and can support a dual-site supply strategy.
Located in Marlborough, MA, close to Cambridge/Boston biotech hub, we supply small-scale, high-quality samples on short timelines. The same quality standard applies from U.S. lab samples to larger-scale lab and GMP manufacturing in Japan so there is no quality gap as your program advances.
Our sample quality is consistent with the larger-scale lab and GMP materials produced in Japan - enabling a smooth path from early screening to later-stage development.
Rapid mg-scale delivery
From our Marlborough, MA lab near the Cambridge/Boston biotech hub, SC-AMSA provides non-GMP, milligram-scale gRNA samples for screening and in vitro/in vivo studies. Fast turnaround and close, local communication help you progress sequence selection and early development efficiently and smoothly.
HIGH PURITY,
BACKED BY DATA
Every shipment includes an Analytical Data Report (ADR) to support confident decision-making - even at milligram scale, where supporting data is often limited. Using high-resolution RP-HPLC, we can detect n±1-mer related impurities and clearly characterize sample quality. This transparency helps you compare candidates efficiently and progress early development with confidence.
CONSISTENT QUALITY WHEN SCALING
When demand increases or GMP supply is required, manufacturing can transition within the Sumitomo Chemical group in Japan while maintaining a consistent quality standard. Sumitomo Chemical brings over 50 years of small-molecule CDMO experience, a strong quality assurance culture, and a proven record of successful inspections by authorities such as the FDA. PeptiStar, a Sumitomo Chemical-backed affiliate, adds flexible GMP capability for smaller-volume programs, and when volumes grow beyond that range, Sumitomo Chemical can support larger-scale manufacturing̶ helping prevent quality gaps as your program advances.
LONG RNA, COMPLEX MODIFICATIONS - SUPPORTED
Our chemistry platform has demonstrated gRNA synthesis capability up to ~250 mer, enabling designs well beyond 100 mer. We also have experience with a broad range of chemical modifications, including less common options. If you are exploring longer sequences or unusual modification patterns, please share your design, our team will propose the most suitable approach.
About SC-AMSA
Sumitomo Chemical Advanced Medical Solutions America LLC (SC-AMSA) is a U.S. subsidiary within the Sumitomo Chemical Group, established to support genome-editing programs in the Cambridge/Boston ecosystem. Based in Marlborough, Massachusetts, we provide non-GMP, milligram-scale gRNA samples for screening and in vitro/in vivo studies, with fast turnaround and direct scientist-to-scientist communication. Each shipment is supported by an Analytical Data Report (ADR) to enable clear, data-driven decisions. As programs advance, we coordinate within the Sumitomo Chemical Group’ s capabilities --including PeptiStar-- to support the next stage of development. [Contact us] to discuss your gRNA sample needs.
Why Boston?
Sumitomo Chemical is one of Japan’ s largest integrated chemical companies, built on a long history, broad manufacturing capabilities, and a strong quality mindset. At the same time, genome editing programs in the Cambridge/Boston ecosystem move at exceptional speed requiring rapid iterations, clear data, and direct technical dialogue. To support these fast-moving teams without compromising reliability, we chose to establish SC-AMSA in Marlborough, Massachusetts, close to our customers. From our Boston-area lab, we provide milligram-scale, non-GMP gRNA samples with short turnaround and scientist-to-scientist communication so your development can progress efficiently and with confidence.
Company Profile
| Companyname | Sumitomo Chemical Advanced Medical Solutions America LLC (SC-AMSA) |
|---|---|
| Location | 84 Waterford Drive, Marlborough, MA 01752, USA |
| President | Katsuyuki Imada |
| Established | April 1, 2025 |
| Ownership | Sumitomo Chemical Co., Ltd. 99% / Sumitomo Chemical America, Inc. 1% |